New Congenital Neutropenia Syndrome And Causative Gene Mutation Identified By Scientists A team of scientists has discovered a new syndrome associated with severe congenital neutropenia (SCN), a rare disorder in which children lack sufficient infection-fighting white cells, and identified the genetic cause of the syndrome: mutations in the gene Glucose-6-phosphatase, catalytic subunit 3 (G6PC3). The findings, which are published in the Jan.
Antioxidants Offer Pain Relief In Patients With Chronic PancreatitisAntioxidant supplementation was found to be effective in relieving pain and reducing levels of oxidative stress in patients with chronic pancreatitis (CP), reports a new study in Gastroenterology. CP is a progressive inflammatory disease of the pancreas in which patients experience abdominal pain (in early stage) and diabetes and maldigestion (in late stage).
Novartis Strengthens Vaccine Pipeline With Agreement For Novel CMV Vaccines CandidateNovartis has strengthened its vaccines pipeline through an exclusive agreement to license AlphaVax' investigational Cytomegalovirus (CMV) vaccine program. This CMV agreement adds to Novartis' promising early stage pipeline of novel vaccines, which focuses on significant unmet needs for the prevention of fatal diseases such as meningococcal infections and other hospital and community acquired infections.
Study Shows Correlation In New Mexico Between Childhood Immunization Rates And Medicaid EnrollmentNew Mexico has the highest proportion of children in the nation enrolled in Medicaid. An article published in the online, open-access journal PLoS ONE highlights research showing that childhood immunization rates in the state suffered when barriers increased to children's receiving Medicaid coverage. Researchers at the University of Toronto, University of New Mexico, and New Mexico Department of Health conducted the study. Dr.
Diamyd Medical: New Study Application To Vaccinate Against Juvenile Diabetes With Diamyd®Diamyd Medical AB (publ.) (Pink Sheets:DMYDY) (STO:DIAMB): A renowned research group at Lund University has filed an application with the Swedish Medical Products Agency to carry out a study of the diabetes vaccine Diamyd® for the prevention of type 1 diabetes in Swedish children. This is the second prevention study with the diabetes vaccine Diamyd® for which approval has been sought in a short period.
Cancer Drug Effectively Treats Transplant RejectionsUniversity of Cincinnati (UC) researchers have discovered a new therapy for transplant patients, targeting the antibody-producing plasma cells that can cause organ rejection. Results of the study are published in the Dec. 27, 2008, edition of the journal Transplantation.
UT Public Health Researchers Find Link To Severe Staph Infections Researchers at The University of Texas School of Public Health recently described studies that support the link between the severity of community-acquired antibiotic-resistant Staphylococcus aureus (CA MRSA) infections and the Panton Valentine leukocidin (PVL). The Panton Valentine leukocidin is made up of two components - LukF-PV and LukS-PV - and is typically produced by community-acquired methicillin-resistant S. aureus (CA MRSA).
ImmunoCellular Therapeutics' Cancer Vaccine Demonstrates Immune Response Against Brain Cancer In Clinical TrialImmunoCellular Therapeutics, Ltd. (OTCBB:IMUC) (IMUC), a biotechnology company, presented preliminary, promising clinical data from a Phase I trial, evaluating ICT-107, the company's dendritic cell-based cancer vaccine product candidate for the treatment of glioblastoma. ICT-107 was well tolerated, and no significant adverse events were reported. These data were reported at the Society for Neuro-Oncology 13th Annual Scientific Meeting in Las Vegas, Nevada.
Scientists Reveal Structure Of New Botulism Nerve Toxin Subtype Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have determined the atomic-level structure of a third subtype of botulinum neurotoxin - a deadly toxin produced by certain bacteria that causes the disease botulism, and is also used in cosmetic and therapeutic applications such as reducing wrinkles and calming a hyperactive bladder.
Potential Autoimmunity-Inducing Cells Found In Healthy Adults It's not just patients with autoimmune diseases like lupus and rheumatoid arthritis (RA) that have self-attacking immune cells - healthy people have them too, according to a new report in the Journal of Experimental Medicine. In healthy adults, however, these cells are maintained in an 'off' state, perhaps explaining their innocuous nature.
Immune Cells Contribute To The Development Of Parkinson's Disease Parkinson disease is a neurodegenerative disorder that impairs movement, balance, speech, and other functions. It is characterized by the loss of nerves in the brain that produce a substance known as dopamine. Although the loss of dopamine-containing nerves is accompanied by accumulation of immune cells known as T cells, these accumulating T cells were not thought to have a role in the development of disease. However, Stéphane Hunot, Etienne C.
Immune Cells Implicated In Parkinson's DiseaseScientists in France and the US discovered that a type of immune system cell may facilitate the development of Parkinson's Disease and that targetting part of the immune system with drugs could be a new way to treat the disease.
Study Of New Drug To Stimulate Immune System Of Cancer Victims: TGen, Scottsdale Healthcare, Mayo ClinicThe Translational Genomics Research Institute (TGen), Scottsdale Healthcare and Mayo Clinic are testing a new drug that could help cancer patients by stimulating the immune system. Clinical trials of the drug VTX-2337 are being conducted at TGen Clinical Research Services at Scottsdale Healthcare, a partnership of Phoenix-based TGen and Scottsdale-based Scottsdale Healthcare Corp., and at Mayo Clinic in Arizona. Dr.
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