Lung Cancer Cells Activate Inflammation To Induce MetastasisA research team from the University of California, San Diego School of Medicine has identified a protein produced by cancerous lung epithelial cells that enhances metastasis by stimulating the activity of inflammatory cells. Their findings, to be published in the January 1 issue of the journal Nature, explain how advanced cancer cells usurp components of the host innate immune system to generate an inflammatory microenvironment hospitable for the metastatic spread of lung cancer.
In Lung Cancer, Silencing One Crucial Gene Disrupts Normal Functioning Of GenomeWhile examining patterns of DNA modification in lung cancer, a team of international researchers has discovered what they say is a surprising new mechanism. They say that "silencing" of a single gene in lung cancer led to a general impairment in genome-wide changes in cells, contributing to cancer development and progression.
In Lung Cancer, Silencing One Crucial Gene Disrupts Normal Functioning Of GenomeWhile examining patterns of DNA modification in lung cancer, a team of international researchers has discovered what they say is a surprising new mechanism. They say that "silencing" of a single gene in lung cancer led to a general impairment in genome-wide changes in cells, contributing to cancer development and progression. In the January 1, 2009, issue of
SNPs Of ABC Transporter Genes Linked To Lung Cancer Risk Individuals with particular variants of certain genes involved in metabolizing the most potent carcinogen found in cigarette smoke have an increased risk of developing lung cancer. That is the conclusion of a new study published in the February 1, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer Society. The study's results may help shed light on how lung cancer develops and could have important implications for preventing smoking-related cancers.
Common Food Additive Found To Increase Risk And Speed Spread Of Lung CancerNew research in an animal model suggests that a diet high in inorganic phosphates, which are found in a variety of processed foods including meats, cheeses, beverages, and bakery products, might speed growth of lung cancer tumors and may even contribute to the development of those tumors in individuals predisposed to the disease. The study also suggests that dietary regulation of inorganic phosphates may play an important role in lung cancer treatment.
Family Members Of Critically Ill Patients Want To Discuss Loved Ones' Uncertain PrognosesCritically ill patients frequently have uncertain prognoses, but their families overwhelmingly wish that physicians would address prognostic uncertainty candidly, according to a new study out of the University of San Francisco Medical Center. "Our interviews revealed that caregivers appear to believe that some uncertainty is unavoidable, and just the nature of life," said lead author Douglas White, M.D., M.A.S.
PharmaMar Announces The Initiation Of Phase II Studies With Irvalec® PharmaMar, a biotechnology company from Zeltia Group, announces the initiation of a Phase II multicenter study of Irvalec® in patients with non- microcitic lung cancer. The study will test the therapy in patients who have undergone platinum based chemotherapy. Lung cancer is the main cause of death by cancer. There are different types of the disease.
Merck Serono Acquires Manufacturing Rights And Facility For Stimuvax From Oncothyreon Merck Serono, a division of Merck KGaA, announced recently that it has modified the license from Oncothyreon to include the right to manufacture Stimuvax® (BLP25 liposome vaccine) and also has purchased current inventory and certain assets used for the manufacture of Stimuvax from Oncothyreon Inc. (Nasdaq: ONTY) (TSX:ONY) for a total amount of approximately US$13 million.
American Lung Association Offers Seven Tips To Quit Smoking This New YearMany people will make New Year's resolutions to quit smoking this year. With the economy in turmoil, quitting smoking is not only good for your health, but also your wallet. Having a solid smoking cessation plan can greatly improve one's chance for success. The American Lung Association offers tips and resources that have helped thousands of people give up smoking for good: 1.
Ovarian, Breast And Lung Cancer Survival Linked To Two Proteins US scientists found that levels of two proteins called Dicer and Drosher that are involved in shutting down genes were linked to a woman's chances of surviving ovarian cancer and similar effects were also found in lung and breast cancer patients. Women with high levels of these proteins had a median survival of 11 years while women with low levels of both proteins only had a median survival rate of 2.7 years.
Lung Cancer Screening Feasibility Study FundedA study to assess the feasibility of undertaking a UK-based screening trial for lung cancer has been commissioned by the National institute for Health Research Health Technology Assessment (NIHR HTA) programme. Lung cancer kills more people worldwide than any other malignancy accounting for around 1.4 million deaths each year, and around 38,000 individuals are diagnosed with the disease in the UK each year.
International Tobacco Control Leaders Recognized By American Cancer SocietyThe American Cancer Society has announced the winners of the 2009 Luther L. Terry Awards for Exemplary Leadership in Tobacco Control. The awards are named for the late United States Surgeon General Luther L. Terry, M.D., who led the landmark 1964 Surgeon General's Report which connected tobacco use to lung cancer and other illnesses. Dr. Terry's courageous and groundbreaking work established the foundation for public health scrutiny of the dangers of tobacco use.
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