Cystic Fibrosis Patients' Self-assessment Of Health Can Predict Prognosis
Adult Cystic Fibrosis patients can provide important information that helps to predict their prognosis, according to research that asked 223 adult CF patients to assess their own health and well-being. "We wished to see whether patients themselves had clinically relevant insight to their disease, and we found that they did," said lead author of the study, Janice Abbott, Ph.D., of the University of Central Lancashire in England.

Cystic Fibrosis Patients' Self-Assessment Of Health Can Predict Prognosis
Adult Cystic Fibrosis patients can provide important information that helps to predict their prognosis, according to research that asked 223 adult CF patients to assess their own health and well-being. "We wished to see whether patients themselves had clinically relevant insight to their disease, and we found that they did," said lead author of the study, Janice Abbott, Ph.D., of the University of Central Lancashire in England.

Evolutionary Roots Of Ancient Bacteria May Open New Line Of Attack On CF
The redox-active pigments responsible for the blue-green stain of the mucus that clogs the lungs of children and adults with cystic fibrosis (CF) are primarily signaling molecules that allow large clusters of the opportunistic infection agent, Pseudomonas aeruginosa, to organize themselves into structured communities, reported Massachusetts Institute of Technology geobiologists at American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.

Cystic Fibrosis Services Pharmacy Celebrates 20th Anniversary
Cystic Fibrosis Services, Inc., a wholly owned subsidiary of the Cystic Fibrosis Foundation, today announced its 20th anniversary of providing quality pharmacy services to the cystic fibrosis (CF) community nationwide. The organization was founded in 1988 with one patient, one prescription and a mission to improve access to specialty medications for people with CF. It met an untapped need and had 1,300 customers within six months.

Ancient Bacteria Offer New Line Of Attack On Cystic Fibrosis
MIT researchers have found that the pigments responsible for the blue-green stain of the mucus that clogs the lungs of cystic fibrosis (CF) patients are primarily signaling molecules that allow large clusters of the opportunistic infection agent, Pseudomonas aeruginosa, to organize themselves into structured communities.

Official Opening For New Adult Cystic Fibrosis Unit, St James's University Hospital, Leeds, England
The doctor who pioneered the treatment for cystic fibrosis patients in Yorkshire will be returning to St James's University Hospital in Leeds on Tuesday (16 December) to officially open the new Regional Adult Cystic Fibrosis Unit in the hospital's Gledhow Wing.

Intervention In Infants With Cystic Fibrosis Key To Slowing Progression
Early detection of lung disease in cystic fibrosis (CF), combined with aggressive treatment in infants, may be the key to controlling the progression of the disease, according to a recent study. New research shows that contrary to previous scientific opinion, progressive lung damage in CF patients can begin as early as infancy even though lung function shortly after diagnosis is normal.

Viral DNA In Bacterial Genome Could Hold Key To Novel Cystic Fibrosis Treatments
The bacterium Pseudomonas aeruginosa is well known for its environmental versatility, ability to cause infection in humans, and its capacity to resist antibiotics. P. aeruginosa is the most common cause of persistent and fatal lung infections in cystic fibrosis patients. In a study published online today in

Prenatal Blood Testing Could Detect Fetal Disorders, Study Says
A noninvasive prenatal blood test could detect whether a fetus will have genetic disorders such as cystic fibrosis or sickle cell anemia, according to a study published online in the Proceedings of the National Academy of Science, the Wall Street Journal reports.

Prenatal Diagnostic Technology Allows Diagnosis Of Inherited Diseases Such As Cystic Fibrosis Caused By Single Gene Mutations
Sequenom, Inc. (NASDAQ:SQNM), announced that breakthrough data from a collaborative project with The Chinese University of Hong Kong, supporting the noninvasive prenatal diagnosis of monogenic diseases, were published online today in the Early Edition of the Proceedings of the National Academy of Sciences.

Journal Of Clinical Investigation Table Of Contents: Nov. 20, 2008
Preventing tumor cells from refueling: a new anticancer approach? New data, generated in mice, by Pierre Sonveaux and colleagues, at Université catholique de Louvain, Belgium, have identified a potential new target for anticancer therapeutics. Not all cells in a tumor are equal, for example, some are in regions rich in oxygen, whereas others are in regions deprived of oxygen (hypoxic regions).

Agent Used To Treat Brain Infarction Might Be Useful For Lung Injury
The average mortality rate of idiopathic pulmonary fibrosis (IPF) is estimated to be 50.8 per 1,000,000 people per year. The mortality rate is now higher than recent mortality rates for a number of malignancies. Although IPF should no longer be considered a rare disease, there is no established treatment that definitely improves its outcome. Furthermore, about 10% of IPF causes a very rapid progression called "acute exacerbation".

Vertex Pharmaceuticals Highlights Cystic Fibrosis Program Targeting The CFTR Protein Responsible For Cystic Fibrosis
VX-770 Based on data presented to date, Vertex intends to work with global regulatory authorities on the design of a registration program for VX-770 which, if agreed upon, could begin in the first half of 2009.

Publication Announcement - Carrier Screening For CF In US Genetic Testing Laboratories: A Survey Of Laboratory Directors
Market pressures may have more influence on clinical practice than laboratory guidelines: That's one conclusion of a Center survey, which found that guidelines for cystic fibrosis (CF) carrier screening have only been partially adopted.

Adapting To Life With The Risk Or Reality Of Genetic Disease: Genetic Counselors Suggest Ways To Help Patients Cope
If you are afflicted with a genetic disease -- or at risk of developing one -- how do you handle it? Do you tell your loved ones? What is the best way to cope? If your loved one has a genetic disorder, how do you best adapt? New research funded by the National Human Genome Research Inst